Metallothionein – Aquatic Toxicology

MULTIPLE CHOICE QUESTIONS:

  • Metallothionein was discovered in – by Margoshes and Vallee.

a.1822

b.1765

c.1957

d.1947

  • The molecular mass of metallothionein is

a.2-4kDa

b.2-3kDa

c-7-8kDa

d.6-8kDa

  • The molecule of MT is made up of – Amino acids.

a.10

b.61

c.45

d.80

  • They are very stable and bind to metals via metal-

a.Thiolate bonds

b.hydrogen bond

c.sulphur bond

d.double bond

  • The main function of MT is to regulate the metabolically important metals such as-

a.Al

b.Cu and Zn

c.Hg

d.Fe

  • The fish MT is more thermal sensitive than- MT.

a.reptiles MT

b.amphibian MT

c.birds MT

d.mammalian MT

  • Scientific name of Turbot is:

a) Cyprinus carpio 

 b) Solea Solea

c) Scophthalmus Maximus

  •  Scientific name of Carp is:

a) Cyprinus carpio 

b) Solea Solea

c) Oncorhynchus mykiss

 d) Danio rerio

  • 3) Scientific name of Gold fish is:

a) Solea Solea 

b) Danio rerio

c)Carassius Auratus

  • Onchorynchus mykiss is:

     a) Tilapia

     b) Rainbow trout

     c) Sole  

     d) Gold fish

  •  Increase in metallothionein level is the _________ response to the extent of heavy metals.

   a) Direct

   b) Indirect

   c) None

  •  King and Olsson characterized the____ metallothionein genes:

    a) 1

     b) 2

     c) 3  

     d) 4

  •  The four metallothionein genes share common regions:

      a) promoter  

      b) accelerator

       c) reactor

       d) None

  •  Metal responsive elements effectively bind ____

       a) MTs 

       b) MTF 

       c) both 

       d) None

  • _____ contains a large number of proteins that carryout metabolic transformation

        a) Cytochrome P450

        b) CO- Fe  

        c) both