Aquatic Toxicology Part-9

  1. This is an programmed cell death process that occurred in multicellular organisms.
    1. Necrosis
    2. Lysis
    3. Apoptosis
    4. Senescence
  2. Apoptotic bodies can be recognized with the presence of these on the surface
    1. Phosphatidyl tyrosine
    2. Phosphatidyl inositol
    3. Phosphatidyl choline
    4. Phosphatidyl serine
  3. This is concerned with the intrinsic pathway of apotosis
    1. Cytochrome d
    2. Cytochrome c
    3. Cytochrome b
    4. Cytochrome a
  4. Apoptotic cell death due to the inactivation of this
    1. Pkc
    2. PKB
    3. RAF1
    4.  
  5. Shrinking of the neucleus is caused when this inactivates
    1. Gelsolin
    2. Tubulin
    3. Actin
    4. Lamin
  6. This cell organelle participate in animal apoptosis
    1. Neucleus
    2. Vacuole’s
    3. Mitochondria
    4. Chloroplast
  7. This can stimulate cytochrome release from mitochondria
    1. Akt
    2. BID
    3. BAD
    4. SMAC
  8. This can not be killed by apoptosis
    1. Immune cell
    2. Cell with DNA damage
    3. Cancer cells
    4. A cell infected with viruses
  9. This is an anti apoptotic protein
    1. BIM
    2. Xs
    3. Bfl 1
    4. NOXA
  10. This is an extracellular messenger of apoptosis
    1. Tumor necrosis factor
    2. Serine
    3. Translation inhibitor
    4. Ribozymes
  11. …………….. single transduction pathway in mechanism of apoptosis
    1. 1
    2. 2
    3. 3
    4. 4
  12. Anti apoptotic molecule………………present on the surface of membrane
    1. Bfl1
    2. xs
    3. Bcl2
    4. Noxa
  13. Anti apoptotic molecule bcl2 inhibits the pro apoptotic molecule…………
    1. Bh3
    2. Bfl1
    3. xs
    4. None of above
  14. Stimuli that initiate intracellular signals
    1. Radiation
    2. Absence of growth factor
    3. Hormones
    4. All of these
  15. In the absence of growth factor anti apoptotic molecule Lost and………become activated which start leakage of cytochrome c
    1. MOMP
    2. TNF
    3. 1
    4. Bh3
  16. Cytochrome c binds with …………….as well casepase .9 forming apoptostom
    1. MOMP
    2. APaf 1
    3. Both
    4. None of above
  17. Extrinsic pathway initiate …………. Signals
    1. Intracellular
    2. Extracellular
    3. Both a and b
    4. None of above
  18. Intrinsic pathway initiate …………….. signals
    1. Intracellular
    2. Extracellular
    3. Both
    4. None
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